Herds of wildebeest, swarms of bees, and schools of fish all provide mesmerizing displays of coordinated motion. Fish, birds, and other animals numbering even in the millions can act as one not through centralized control, but through local actions and decisions, as each individual assesses the speed and orientation of its neighbors. This self-organization is … Continue reading How can a swarm swarm? — What is biophysics? #13
It’s time for my recap of notable books I read in the past year. (Previous posts: 2021, 2020, 2019, 2018, 2017, 2016, and 2015.) The biggest difference between 2022 and years past is audiobooks, which made up 17 of the 50 books I “read” (consumed?). I had listened to audiobooks before, but very few, and … Continue reading The Year in Books, 2022, in which I discovered audiobooks
This past term, Fall 2022, I taught for the second time a course I created on image analysis. (Syllabus.) The structure and content were similar to last year’s — last year went well, and I put lots of work into it, so “if it ain’t broke…” Here’s a summary of things in the 2021 course … Continue reading Image Analysis Course Recap, Fall 2022
In science there are experiments that try to construct simple, tractable models of complex phenomena, with the goal of developing insights that will be relevant to the more complicated systems. Alternatively, there are experiments that try to infer insights amid a flurry of coexisting factors. Each of these approaches has its merits and flaws. I … Continue reading How to build a gut microbiome in 119 easy steps
[Announcement: I’m giving I gave a virtual book talk Tuesday, Nov 29, 2022! Video recording link.] Many living things move. Panthers pounce, snakes slither, dolphins dive. Organs can move (such as beating hearts), and even individual cells can be motile, such as the immune cells that crawl through our tissues. How far down in scale … Continue reading Can a Molecule Walk? — What is biophysics? #12
This was supposed to be a short, simple post about how brittle stars use their skeletons to help them see. It turns out, however, that the brittle stars have misled us, and what we thought we knew twenty years ago has been overturned by new observations. The question of what and how various creatures see … Continue reading Do Sea Stars See? — What is biophysics? #11
Four years ago, I read Bryan Caplan’s The Case against Education: Why the Education System Is a Waste of Time and Money, a polemic about the form of education in the U.S. I disagreed strongly with a decent fraction of it, agreed strongly with a larger fraction of it, and overall found it stimulating — … Continue reading The Case For, and the Case Against, “The Case Against Education”
About a recent paper from my lab: Deepika Sundarraman, T. Jarrod Smith, Jade V. Z. Kast, Karen Guillemin, and Raghuveer Parthasarathy, “Disaggregation as an interaction mechanism among intestinal bacteria,” Biophysical Journal (2022). Some bacteria stick together; others do not. We have seen these variations among bacteria inside the zebrafish gut, and it’s probably the case … Continue reading Things Fall Apart; The Bacterial Cluster Cannot Hold
Your genome is the totality of your genetic instructions, embodied in your DNA, of which each cell carries a copy. (Two copies, but let’s ignore that.) How big is your genome? Often, the answer is given in terms of base pairs — the rungs of the ladder of double-stranded DNA. For humans, it’s 3 billion … Continue reading How Big Is Your Genome? — What is biophysics? #10
On his blog today, Andrew Gelman posted a simple to state, clearly realistic, and surprisingly deep statistics puzzle sent to him by Ariel Rubinstein and Michele Piccione, from their paper, “Real People Aggregating Signals: An Experiment and a Short Story” Article Link: A very small proportion of the newborns in a certain country have a … Continue reading Three views of a statistics puzzle
The Eighteenth Elephant 